SmartFlow® Cannula
The SmartFlow® MR Compatible Ventricular Cannula has received 510(k) clearance from the FDA for use in the US for the aspiration of CSF, or injection of the chemotherapy drug Cytarabine into the ventricle. It has also been CE marked for use in Europe for the delivery of approved fluids into the brain or aspiration of CSF. It’s being utilized in approved clinical and preclinical studies for various research and drug trials. This device is not intended for implant and is intended for single patient use only.
With over 8,000 cannulas sold to-date, SmartFlow is
the industry-leading cannula for intraparenchymal drug delivery trials
- The SmartFlow MRI-Safe Cannula can be used to bypass the blood brain barrier by delivering therapeutics to regions of interest
- Used in trials to infuse gene therapy, viruses, or oncolytic agents via Convection Enhanced Delivery (CED), and deposit stem cells
Bilateral Cannulas Allow for Simultaneous Infusion
Why is MR Compatibility Important?
- MRI provides real-time confirmation of cannula placement and infusate coverage
- Allows for accurate dosing to regions of interest in the brain
- Enables intra-procedural adjustments to improve distribution
- Allows for comparison of patient outcomes to infusion parameters
SmartFlow Cannula Construction
- Single Silica Inner Lumen: Extends throughout length to enable low-volume priming and prevent leaks
- Cannula Body: Rigid for precise placement and control
- Proprietary, non-PVC, latex-free, DEHP-free extension tubing with female luer connector
Stepped distal tip and lumen sizes of 0.2 or 0.5mm for reduced reflux, minimal priming/dead volume, and precision:
SmartFlow Cannula Benefits
- Integrated 4ft or 10ft tubing allow syringe/pump operation away from the patient and magnetic field
- Multiple off-the-shelf configurations empower specific applications, and all parameters are customizable: